Healthy men who took Viagra, Cialis see end of study
Sunday, July 15th, 2012Healthy men who took Viagra or Cialis every day for six months has not significantly developed vision problems, U.S. researchers said Monday in a study funded by the company to respond to popular concerns about impotence treatments.
The drugs work by blocking the action of the enzyme phodiesterase type 5 or PDE5 the blood vessels in the penis. However, inhibitors of PDE5 May also affect blood vessels in the retina, which could explain some of the reports of vision problems.
To test this, a team led by Dr. William Cordell of Lilly Research Laboratories in Indianapolis, and colleagues conducted a randomized study to find changes in the retina in Men Taking Viagra or Cialis.
They studied 244 Healthy Men or those of a mild erectile dysfunction aged 30 to 65 who had no vision problems. Among them,
- 85 have 5 milligrams of Cialis,
- 77 took 50 mg of sildenafil,
- 82 took a dummy pill every day for six months.
The men have been reviews of the global view, including electroretinography, a test to measure the electrical response of cells sensitive to light in the eye before, during and after treatment.
Among the 194 men who completed the study, researchers found no significant difference between treatment and placebo on electroretinography, tests of visual function, measurements of pressure within the eyeball or the evaluation of the anatomy of the eye.
“Our results indicate that there was no damage or the cumulative effect of the clinic,” for the dose of either study drug, the researchers wrote in the Archives of Ophthalmology.
They said their study was limited because the doses used were lower than other studies have found that the retinal changes. And he said that the results can not be generalized to men with eye problems, which were excluded from the study.
Viagra and Cialis each have global sales of over $ 1 billion in 2008.